File:In-Vivo-Approaches-Reveal-a-Key-Role-for-DCs-in-CD4+-T-Cell-Activation-and-Parasite-Clearance-ppat.1004598.s017.ogv

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In-Vivo-Approaches-Reveal-a-Key-Role-for-DCs-in-CD4+-T-Cell-Activation-and-Parasite-Clearance-ppat.1004598.s017.ogv (Ogg Theora video file, length 22 s, 580 × 479 pixels, 1.55 Mbps, file size: 4.12 MB)

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English: Subcapsular RP DCs containing iRBC remnants and in the process of phagocytizing an iRBC during pre-crisis. The animation shows a representative 3D region of the subcapsular RP of the spleen in a B6.CD11c-YFP mouse, starting five days after i.p. infection with 1 × 106 mature mCherry-Pc iRBCs. The video was made at a time of day when mature parasite stages predominated, mCherry-Pc iRBC remnants inside YFP+ cells can be observed as yellow spots of merged mCherry/YFP-3D signal. It was possible to observe in 3D ongoing phagocytosis of an mCherry-Pc iRBC by a YFP+ cell. The white arrows indicate the ongoing phagocytosis described above. The video is shown at 10 frames/s with maximum color intensity.
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Source S10 Video from Borges da Silva H, Fonseca R, Cassado A, Machado de Salles É, de Menezes M, Langhorne J, Perez K, Cuccovia I, Ryffel B, Barreto V, Marinho C, Boscardin S, Álvarez J, D’Império-Lima M, Tadokoro C (2015). "In Vivo Approaches Reveal a Key Role for DCs in CD4+ T Cell Activation and Parasite Clearance during the Acute Phase of Experimental Blood-Stage Malaria". PLOS Pathogens. DOI:10.1371/journal.ppat.1004598. PMID 25658925. PMC: 4450059.
Author Borges da Silva H, Fonseca R, Cassado A, Machado de Salles É, de Menezes M, Langhorne J, Perez K, Cuccovia I, Ryffel B, Barreto V, Marinho C, Boscardin S, Álvarez J, D’Império-Lima M, Tadokoro C
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Date/TimeThumbnailDimensionsUserComment
current17:37, 12 October 201622 s, 580 × 479 (4.12 MB)Open Access Media Importer Bot (talk | contribs)Automatically uploaded media file from Open Access source. Please report problems or suggestions here.

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Format Bitrate Download Status Encode time
VP9 360P 394 kbps Completed 15:12, 29 August 2018 17 s
VP9 240P 222 kbps Completed 15:12, 29 August 2018 11 s
WebM 360P 504 kbps Completed 17:37, 12 October 2016 12 s
QuickTime 144p (MJPEG) 403 kbps Completed 18:39, 5 November 2024 1.0 s

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