File:Functional-Rotation-of-the-Transporter-AcrB-Insights-into-Drug-Extrusion-from-Simulations-pcbi.1000806.s011.ogv
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Size of this JPG preview of this OGG file: 800 × 488 pixels. Other resolutions: 320 × 195 pixels | 640 × 391 pixels | 1,024 × 625 pixels | 1,314 × 802 pixels.
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[edit]DescriptionFunctional-Rotation-of-the-Transporter-AcrB-Insights-into-Drug-Extrusion-from-Simulations-pcbi.1000806.s011.ogv |
English: Movement of doxorubicin and of the four subdomains PC1, PC2, PN1, PN2 extracted from one TMD simulation along the T→O transition. Firstly the whole trimer is shown, then zoom is performed on the T monomer, in the region around the drug. Doxorubicin is shown initially in blue, and becomes red following the TMD time. Some residues of the binding pocket are also highlighted. |
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Source | Video S1 from Schulz R, Vargiu A, Collu F, Kleinekathöfer U, Ruggerone P (2010). "Functional Rotation of the Transporter AcrB: Insights into Drug Extrusion from Simulations". PLOS Computational Biology. DOI:10.1371/journal.pcbi.1000806. PMID 20548943. PMC: 2883587. | ||
Author | Schulz R, Vargiu A, Collu F, Kleinekathöfer U, Ruggerone P | ||
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 18:32, 16 November 2012 | 50 s, 1,314 × 802 (8.4 MB) | Open Access Media Importer Bot (talk | contribs) | Automatically uploaded media file from Open Access source. Please report problems or suggestions here. |
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Usage terms | http://creativecommons.org/licenses/by/3.0/ |
Image title | Movement of doxorubicin and of the four subdomains PC1, PC2, PN1, PN2 extracted from one TMD simulation along the T?O transition. Firstly the whole trimer is shown, then zoom is performed on the T monomer, in the region around the drug. Doxorubicin is shown initially in blue, and becomes red following the TMD time. Some residues of the binding pocket are also highlighted. |
Software used | Xiph.Org libtheora 1.1 20090822 (Thusnelda) |
Date and time of digitizing | 2010-06 |