File:St-Johns-Wort-(Hypericum-perforatum-L.)-Photomedicine-Hypericin-Photodynamic-Therapy-Induces-pone.0103762.s004.ogv
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[edit]DescriptionSt-Johns-Wort-(Hypericum-perforatum-L.)-Photomedicine-Hypericin-Photodynamic-Therapy-Induces-pone.0103762.s004.ogv |
English: Hypericin-PDT induced loss of structural details of OTC-GFP positive structures (mitochondria). Cells expressing OTC-GFP (green) were exposed to 3 µM hypericin (red) for 4 h followed by light-activation with live confocal fluorescent time-lapse microscopy. A cellular region (red box) was bleached with the 561 nm excitation wavelength to activate hypericin. Nuclei were counterstained with Hoechst (blue). A representative time-lapse result is shown (n = 3, scale bars: 20 µm). |
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Source | Video S1 from Kleemann B, Loos B, Scriba T, Lang D, Davids L (2014). "St John's Wort (Hypericum perforatum L.) Photomedicine: Hypericin-Photodynamic Therapy Induces Metastatic Melanoma Cell Death". PLOS ONE. DOI:10.1371/journal.pone.0103762. PMID 25076130. PMC: 4116257. | ||
Author | Kleemann B, Loos B, Scriba T, Lang D, Davids L | ||
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This file is licensed under the Creative Commons Attribution 4.0 International license.
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current | 22:20, 8 August 2014 | 5.0 s, 1,162 × 1,155 (5.02 MB) | Open Access Media Importer Bot (talk | contribs) | Automatically uploaded media file from Open Access source. Please report problems or suggestions here. |
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Author | Kleemann B, Loos B, Scriba T, Lang D, Davids L |
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Usage terms | http://creativecommons.org/licenses/by/4.0/ |
Image title | Hypericin-PDT induced loss of structural details of OTC-GFP positive structures (mitochondria). Cells expressing OTC-GFP (green) were exposed to 3 µM hypericin (red) for 4 h followed by light-activation with live confocal fluorescent time-lapse microscopy. A cellular region (red box) was bleached with the 561 nm excitation wavelength to activate hypericin. Nuclei were counterstained with Hoechst (blue). A representative time-lapse result is shown (n |
Software used | Xiph.Org libtheora 1.1 20090822 (Thusnelda) |
Date and time of digitizing | 2014 |
Categories:
- Oxidative damage
- Reactive oxygen species
- Videos of cell biology
- Cell membrane
- Intracellular membranes
- Videos of lipid bilayers
- Energy-producing organelles
- Mitochondrial membranes
- Videos of golgi apparatus
- Subcellular localization
- Videos of cell types
- Animal cells
- Molecular cell biology
- Oxidative stress
- Media from PLOS ONE