File:Murid-Herpesvirus-4-Exploits-Dendritic-Cells-to-Infect-B-Cells-ppat.1002346.s003.ogv

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Original file (Ogg Theora video file, length 7.1 s, 2,048 × 1,024 pixels, 7.87 Mbps, file size: 6.7 MB)

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English: Bone marrow-derived DCs were infected with gM-eGFP+ MuHV-4 (3 p.f.u./cell) and imaged 6 h later by time-lapse confocal microscopy (Leica). Images were recorded every 8 sec over 7 min. The left-hand panel shows eGFP fluoresence and the right-hand panel the corresponding phase contrast image. At 6 h after exposure to MuHV-4, DCs show little late lytic gene expression. Thus the eGFP signal comes from the input virions. The non-adherent DCs correspond to those more activated prior to virus exposure, which are poorly infected and so remain eGFP-. The DCs taking up virions, and presumably becoming infected, show flattening, adherence to plastic and marked cytoplasmic motility.
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Source Video S1 from Gaspar M, May J, Sukla S, Frederico B, Gill M, Smith C, Belz G, Stevenson P (2011). "Murid Herpesvirus-4 Exploits Dendritic Cells to Infect B Cells". PLOS Pathogens. DOI:10.1371/journal.ppat.1002346. PMID 22102809. PMC: 3213091.
Author Gaspar M, May J, Sukla S, Frederico B, Gill M, Smith C, Belz G, Stevenson P
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current01:24, 18 November 20127.1 s, 2,048 × 1,024 (6.7 MB)Open Access Media Importer Bot (talk | contribs)Automatically uploaded media file from Open Access source. Please report problems or suggestions here.

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Format Bitrate Download Status Encode time
VP9 1080P 3.81 Mbps Completed 02:24, 4 September 2018 17 s
VP9 720P 1.64 Mbps Completed 02:24, 4 September 2018 8.0 s
VP9 480P 787 kbps Completed 02:24, 4 September 2018 5.0 s
VP9 360P 429 kbps Completed 02:24, 4 September 2018 4.0 s
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WebM 360P 511 kbps Completed 08:08, 19 November 2012 6.0 s
QuickTime 144p (MJPEG) 322 kbps Completed 08:01, 18 November 2024 1.0 s

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