File:Mouse embryo Intravascular trafficking of CX3CR1+ YS pre-macrophages.jpg
Original file (1,780 × 2,460 pixels, file size: 2.62 MB, MIME type: image/jpeg)
Captions
Captions
Summary
[edit]
| Description | Fig 1. Intravascular trafficking of CX3CR1+ YS pre-macrophages. a, b Schematic graphs of the mouse model (a) and the intravital imaging setup in Cx3cr1GFP/+ mice (b). c E16.5 Cx3cr1GFP/+ embryo with surrounding YS and its dense vascular network. d YS tissue with CX3CR1+ pre-macrophages at indicated time points. Pictures show a representative microscopic field of 400 × 400 µm. e Corresponding quantification of CX3CR1+ cells per microscopic field of 400 × 400 µm; *** p < 0.001 (two-tailed Mann–Whitney test); graph shows median with interquartile range (±IQR, error bars). f In vivo YS staining for the endothelial marker CD31 (red) in Cx3cr1GFP/+ (green) embryos at E10.5. g, h, j Images extracted from E10.5 video sequences of CX3CR1+ YS tissue show a cell entering the vasculature (g, from Supplementary Movie 1) as well as intravascular non-adhering (h, from Supplementary Movie 3) and rolling (j) cells. CX3CR1+ cells in focus are indicated by arrowheads; direction of flow from bottom to top (g), left to right (h), left to right (j). i Quantification of intravascular CX3CR1+ cells in the YS in an average-sized vessel; median ± IQR. k Velocity of intravascular non-adhering (n = 50) and rolling (n = 5) CX3CR1+ cells in the YS at E10.5; median ± IQR. Scale bars are 1 mm (c), 100 µm (d, f, g, h, j) |
| Date | |
| Source | https://www.nature.com/articles/s41467-017-02492-2/figures/1 Yolk sac macrophage progenitors traffic to the embryo during defined stages of development. Nat Commun 9, 75 (2018). https://doi.org/10.1038/s41467-017-02492-2 |
| Author | Stremmel, C., Schuchert, R., Wagner, F. et al. |
|
This file, which was originally posted to an external website, has not yet been reviewed by an administrator or reviewer to confirm that the above license is valid. See Category:License review needed for further instructions.
|
Licensing
[edit]
- You are free:
- to share – to copy, distribute and transmit the work
- to remix – to adapt the work
- Under the following conditions:
- attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
Rights and permissions https://www.nature.com/articles/s41467-017-02492-2#citeas Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
File history
Click on a date/time to view the file as it appeared at that time.
| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 20:16, 21 April 2024 | | 1,780 × 2,460 (2.62 MB) | Rasbak (talk | contribs) | {{Information |description=Intravascular trafficking of CX3CR1+ YS pre-macrophages. a, b Schematic graphs of the mouse model (a) and the intravital imaging setup in Cx3cr1GFP/+ mice (b). c E16.5 Cx3cr1GFP/+ embryo with surrounding YS and its dense vascular network. d YS tissue with CX3CR1+ pre-macrophages at indicated time points. Pictures show a representative microscopic field of 400 × 400 µm. e Corresponding quantification of CX3CR1+ cells per microscopic field of 400 × 400 µm; *** p < 0.0... |
You cannot overwrite this file.
File usage on Commons
There are no pages that use this file.
