File:Mouse embryo Intravascular trafficking is independent of MYB and CX3CR1.jpg
Original file (1,360 × 2,512 pixels, file size: 1.84 MB, MIME type: image/jpeg)
Captions
Captions
Summary
[edit]
| Description | Fig 4. Intravascular trafficking is independent of MYB and CX3CR1. a Schematic graph of the Cx3cr1GFP/+ Myb−/− mouse model. b Bright field images of isolated embryos at E16.5 indicating the absence of fetal definitive hematopoiesis (i.e. severe anemia). c, d Visualization (c) and quantification (d) of CX3CR1+ cells in the YS of Myb+/+ or Myb−/− mice at indicated time points; all comparisons of Myb+/+ vs. Myb−/− are n.s. (two-tailed t-test: E9.5 p = 0.9818, E10.5 p = 0.8894, E12.5 p = 0.6900, E16.5 p = 0.9543); mean ± standard deviation (SD, error bars). e Quantification of intravascular CX3CR1+ cells in a Myb+/+ and Myb−/− YS on indicated time points; E10.5: n.s. (two-tailed Mann–Whitney: E10.5 p = 0.4537); median ± IQR. f Quantification of CX3CR1+ cell densities per microscopic field of 400 × 400 µm in embryonic tissues at E10.5; *** p < 0.001 (two-tailed t-test); mean ± SD. g Quantification of intravascular CX3CR1+ cells in YS of Cx3cr1GFP/+ and Cx3cr1GFP/GFP E10.5 embryos; n.s. (two-tailed t-test: p = 0.6065); mean ± SD. Scale bar is 100 µm (c) |
| Date | |
| Source | https://www.nature.com/articles/s41467-017-02492-2/figures/4 Yolk sac macrophage progenitors traffic to the embryo during defined stages of development. Nat Commun 9, 75 (2018). https://doi.org/10.1038/s41467-017-02492-2 |
| Author | Stremmel, C., Schuchert, R., Wagner, F. et al. |
|
This file, which was originally posted to an external website, has not yet been reviewed by an administrator or reviewer to confirm that the above license is valid. See Category:License review needed for further instructions.
|
Licensing
[edit]
- You are free:
- to share – to copy, distribute and transmit the work
- to remix – to adapt the work
- Under the following conditions:
- attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
Rights and permissions https://www.nature.com/articles/s41467-017-02492-2#citeas Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
File history
Click on a date/time to view the file as it appeared at that time.
| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 20:48, 21 April 2024 | | 1,360 × 2,512 (1.84 MB) | Rasbak (talk | contribs) | {{Information |description=Fig 4. Intravascular trafficking is independent of MYB and CX<sub>3</sub>CR1. a Schematic graph of the Cx<sub>3</sub>cr1<sup>GFP/+</sup> Myb<sup>−/−</sup> mouse model. b Bright field images of isolated embryos at E16.5 indicating the absence of fetal definitive hematopoiesis (i.e. severe anemia). c, d Visualization (c) and quantification (d) of CX<sup>3</sup>CR1+ cells in the YS of Myb<sup>+/+</sup> or Myb<sup>−/−</sup> mice at indicated time points; all comparisons... |
You cannot overwrite this file.
File usage on Commons
There are no pages that use this file.
