File:Microenvironmental-Regulation-by-Fibrillin-1-pgen.1002425.s009.ogv
Microenvironmental-Regulation-by-Fibrillin-1-pgen.1002425.s009.ogv (Ogg multiplexed audio/video file, Theora/Vorbis, length 12 s, 640 × 480 pixels, 2.68 Mbps overall, file size: 3.72 MB)
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[edit]DescriptionMicroenvironmental-Regulation-by-Fibrillin-1-pgen.1002425.s009.ogv |
English: Aligned tilt series of immunolabeled fibrillin-1 microfibrils in mutant WMΔ/WMΔ skin. Elastic fiber present in homozygous mutant WMΔ skin shows much reduced periodicity of fibrillin-1 immunogold labeling, indicating disorganized microfibrils. |
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Source | Video S2 from Sengle G, Tsutsui K, Keene D, Tufa S, Carlson E, Charbonneau N, Ono R, Sasaki T, Wirtz M, Samples J, Fessler L, Fessler J, Sekiguchi K, Hayflick S, Sakai L (2012). "Microenvironmental Regulation by Fibrillin-1". PLOS Genetics. DOI:10.1371/journal.pgen.1002425. PMID 22242013. PMC: 3252277. | ||
Author | Sengle G, Tsutsui K, Keene D, Tufa S, Carlson E, Charbonneau N, Ono R, Sasaki T, Wirtz M, Samples J, Fessler L, Fessler J, Sekiguchi K, Hayflick S, Sakai L | ||
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current | 21:29, 17 November 2012 | 12 s, 640 × 480 (3.72 MB) | Open Access Media Importer Bot (talk | contribs) | Automatically uploaded media file from Open Access source. Please report problems or suggestions here. |
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Usage terms | http://creativecommons.org/licenses/by/3.0/ |
Image title | Aligned tilt series of immunolabeled fibrillin-1 microfibrils in mutant WM?/WM? skin. Elastic fiber present in homozygous mutant WM? skin shows much reduced periodicity of fibrillin-1 immunogold labeling, indicating disorganized microfibrils. |
Software used | |
Date and time of digitizing | 2012-01 |
Language | English |
- Model organisms
- Molecular cell biology
- Genetic predispositions to diseases
- Binding sites
- Cellular microenvironment
- Extracellular matrix
- Extracellular matrix proteins
- Latent TGF-beta binding proteins
- Marfan syndrome
- Transgenic mice
- Microfibrils
- Proteases
- Sequence deletion
- Signal transduction
- Skin abnormalities
- Transforming growth factor (TGF)-beta
- Weill-marchesani syndrome