File:MiR-34a-Targeting-of-Notch-Ligand-Delta-Like-1-Impairs-CD15+CD133+-Tumor-Propagating-Cells-and-pone.0024584.s010.ogv

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Original file (Ogg Theora video file, length 9.1 s, 1,388 × 1,040 pixels, 5.47 Mbps, file size: 5.93 MB)

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English: Tumor spheres isolated from Patch1+/- P53-/- mice infected with AdV-miR-34a show sign of induction of differentiation only when they are not dissociated before the infection. At this time, the infected cells remain in contact with each other and are subjected to Notch signaling via the cell non-autonomous pathway. A time-series of phase-contrast brightfield images of the medullpspheres were acquired with an A-Plan Ph1 10× objective for a total time of 72 h, using a Zeiss Axiovert 200M microscope equipped with an Okolab WJ CO2 Microscope Stage Incubator, for controlling the temperature and the %CO2. The time delay between individual images used here was 15 min.
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Source Movie S1 from de Antonellis P, Medaglia C, Cusanelli E, Andolfo I, Liguori L, De Vita G, Carotenuto M, Bello A, Formiggini F, Galeone A, De Rosa G, Virgilio A, Scognamiglio I, Sciro M, Basso G, Schulte J, Cinalli G, Iolascon A, Zollo M (2011). "MiR-34a Targeting of Notch Ligand Delta-Like 1 Impairs CD15+/CD133+ Tumor-Propagating Cells and Supports Neural Differentiation in Medulloblastoma". PLOS ONE. DOI:10.1371/journal.pone.0024584. PMID 21931765. PMC: 3171461.
Author de Antonellis P, Medaglia C, Cusanelli E, Andolfo I, Liguori L, De Vita G, Carotenuto M, Bello A, Formiggini F, Galeone A, De Rosa G, Virgilio A, Scognamiglio I, Sciro M, Basso G, Schulte J, Cinalli G, Iolascon A, Zollo M
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current06:16, 16 November 20129.1 s, 1,388 × 1,040 (5.93 MB)Open Access Media Importer Bot (talk | contribs)Automatically uploaded media file from Open Access source. Please report problems or suggestions here.

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VP9 720P 1.7 Mbps Completed 08:37, 3 September 2018 12 s
VP9 480P 959 kbps Completed 08:36, 3 September 2018 8.0 s
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VP9 240P 304 kbps Completed 08:36, 3 September 2018 6.0 s
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