File:Integrated-Analysis-of-Residue-Coevolution-and-Protein-Structure-in-ABC-Transporters-pone.0036546.s016.ogv

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English: Predicted pairs with separation in sequence. The ribbon represents the polypeptide chain of CFTR in outward-facing conformation, and its colors match with those in Figure 6, 7 and Movie S2, S3. Residues in stick representation, connected by straight black lines, are position pairs predicted to coevolve in the ABC-C family and separated by 4 or fewer positions in sequence. For many pairs the separation occurs at one turn in an -helix (Figure S10A). ATP molecules are shown in sphere representation.
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Source Movie S1 from Gulyás-Kovács A (2012). "Integrated Analysis of Residue Coevolution and Protein Structure in ABC Transporters". PLOS ONE. DOI:10.1371/journal.pone.0036546. PMID 22590562. PMC: 3348156.
Author Gulyás-Kovács A
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