File:Dynamic-Control-of-Cell-Cycle-and-Growth-Coupling-by-Ecdysone-EGFR-and-PI3K-Signaling-in-Drosophila-pbio.1000079.sv002.ogv

English: In the Second Proliferation Stage, Histoblasts Grow and Maintain a Constant Cell Size as the Cell Cycle Slows Down and Divisions Become Asynchronous (16–24 h APF) Cells were labeled using a ubiquitously expressed DE-Cadherin GFP fusion protein. A single cell in the posterior dorsal nest undergoing mitosis was outlined in white and its daughter cells in red and blue. After the first division, the two daughter cells do not divide for 5 h but grow to the size of the mother cell. Subsequently, one of the daughter cells divides again. During this stage, cell divisions occurred stochastically (observe the random distribution of big round cells entering mitosis).