File:Disrupted apical accumulation of RhoA and F-actin after BMP inhibition.png
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| Description | Fig. 6. Disrupted apical accumulation of RhoA and F-actin after BMP inhibition. (A-D) In ovo electroporation of stage 10/11 embryos in the prospective lens and olfactory ectoderm region using a GFP reporter construct alone (A, n =5; C, n =6) or together with a Noggin construct (B, n =7; D, n =7) and cultured to stage 15/16 (lens) and stage 19/20 (olfactory). (A,C) All control embryos show accumulated expression of RhoA and F-actin at the apical region of the cells (A, n =5/5; C, n =6/6). (B,D) Inhibition of BMP signaling disturbed the apical accumulation of RhoA and F-actin in both lens and olfactory epithelial cells (B, n =7/7; D, n =7/7). Boxed regions indicate the areas of higher magnification images. Arrows in C and D indicate the apical side. Scale bars: 100 μm (lower magnification); 10 μm (higher magnification). Ap, apical; Ba, basal. |
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| Source | https://www.researchgate.net/publication/285383324_Apical_constriction_and_epithelial_invagination_are_regulated_by_BMP_activity Vijay Kumar Jidigam, Raghuraman chittoor srinivasan, Lena Gunhaga, Cédric Patthey. Apical constriction and epithelial invagination are regulated by BMP activity. November 2015. Biology Open 4(12). DOI:10.1242/bio.015263 |
| Author | Vijay Kumar Jidigam, Raghuraman chittoor srinivasan, Lena Gunhaga, Cédric Patthey |
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| current | 15:40, 28 October 2024 | | 1,449 × 1,406 (1.67 MB) | Rasbak (talk | contribs) | {{Information |description=Fig. 6. Disrupted apical accumulation of RhoA and F-actin after BMP inhibition. (A-D) In ovo electroporation of stage 10/11 embryos in the prospective lens and olfactory ectoderm region using a GFP reporter construct alone (A, n =5; C, n =6) or together with a Noggin construct (B, n =7; D, n =7) and cultured to stage 15/16 (lens) and stage 19/20 (olfactory). (A,C) All control embryos show accumulated expression of RhoA and F-actin at the apical region of the cells (... |
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