File:Differential-Modulation-of-Retinal-Degeneration-by-Ccl2-and-Cx3cr1-Chemokine-Signalling-pone.0035551.s001.ogv
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[edit]DescriptionDifferential-Modulation-of-Retinal-Degeneration-by-Ccl2-and-Cx3cr1-Chemokine-Signalling-pone.0035551.s001.ogv |
English: C57Bl/6. Animation of 3D-reconstructions (IMARIS) of confocaol Z-stack images taken from the inferior area of a retinal flat mount of a C57Bl/6 mouse at 2 months of age. The volume of the z-stack (x = 183.3 µm, y = 183.3 µm, z = 76 µm) comprises the deep retinal vascular plexus, the outer nuclear layer and part of the inner segments. The deep retinal vascular plexus was labeled with Tritc-lectinB4 and is represented in red, while retinal microglia labeled with Iba1 are shown in green. At the top of the z-stack microglia located at the level of the deep retinal vascular plexus show a normal ramified morphology. These cells are not present in the outer retina. The red and green Imaris surfaces in the area of the inner segments at the bottom of the z-stack represent autofluorescent signals from photoreceptors. |
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Source | Movie S1 from Luhmann U, Lange C, Robbie S, Munro P, Cowing J, Armer H, Luong V, Carvalho L, MacLaren R, Fitzke F, Bainbridge J, Ali R (2012). "Differential Modulation of Retinal Degeneration by Ccl2 and Cx3cr1 Chemokine Signalling". PLOS ONE. DOI:10.1371/journal.pone.0035551. PMID 22545116. PMC: 3335860. | ||
Author | Luhmann U, Lange C, Robbie S, Munro P, Cowing J, Armer H, Luong V, Carvalho L, MacLaren R, Fitzke F, Bainbridge J, Ali R | ||
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 07:12, 16 November 2012 | 20 s, 1,450 × 759 (12.28 MB) | Open Access Media Importer Bot (talk | contribs) | Automatically uploaded media file from Open Access source. Please report problems or suggestions here. |
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Author | Luhmann U, Lange C, Robbie S, Munro P, Cowing J, Armer H, Luong V, Carvalho L, MacLaren R, Fitzke F, Bainbridge J, Ali R |
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Usage terms | http://creativecommons.org/licenses/by/3.0/ |
Image title | C57Bl/6. Animation of 3D-reconstructions (IMARIS) of confocaol Z-stack images taken from the inferior area of a retinal flat mount of a C57Bl/6 mouse at 2 months of age. The volume of the z-stack (x? |
Software used | Xiph.Org libtheora 1.1 20090822 (Thusnelda) |
Date and time of digitizing | 2012 |
Categories:
- Videos of physiology
- Ocular system
- Animal genetics
- Gene function
- Innate immunity
- Animal models of disease
- Vascular biology
- Inherited eye disorders
- Macular disorders
- Videos of disorders of choroid and retina
- Chemokine CCL2
- Inbred C57BL mice
- Knockout mice
- Nerve tissue proteins
- Chemokine receptors
- Videos of retinas
- Retinal degeneration
- Media from PLOS ONE