File:Development-of-proteoglycan-induced-arthritis-depends-on-T-cell-supported-autoantibody-production-ar2954-S2.ogv
From Wikimedia Commons, the free media repository
Jump to navigation
Jump to search
No higher resolution available.
Development-of-proteoglycan-induced-arthritis-depends-on-T-cell-supported-autoantibody-production-ar2954-S2.ogv (Ogg Theora video file, length 5.7 s, 512 × 512 pixels, 4.12 Mbps, file size: 2.78 MB)
File information
Structured data
Captions
Summary
[edit]DescriptionDevelopment-of-proteoglycan-induced-arthritis-depends-on-T-cell-supported-autoantibody-production-ar2954-S2.ogv |
English: Supplemental Video 1. Localization and motility of fluorescent T and B cells in the popliteal LN of a SCID mouse following their transfer from arthritic BALB/c mice. Donor T cells were labeled with CellTracker Red (CMTPX) and non-T cells (~90% B cells) with CellTracker Green (CMFDA), and mixed at a ratio of 1:2 prior to injection into the SCID mouse. The popliteal LN was subjected to TPM imaging on day 7 after cell transfer. Z series of images were acquired from the LN in vivo. Autofluorescent subcapsular sinus macrophages (light blue) are seen in the top layer of the cortex. B cells (green) localize in the more superficial, while T cells (red) in the deeper areas of the LN. Most T and B cells exhibit a polarized shape and 'random' movement. Imaging depth: 87 μm; time elapsed: 9.5 min. |
||
Date | |||
Source | Angyal A, Egelston C, Kobezda T, Olasz K, László A, Glant T, Mikecz K (2010). "Development of proteoglycan-induced arthritis depends on T cell-supported autoantibody production, but does not involve significant influx of T cells into the joints". Arthritis Research & Therapy. DOI:10.1186/ar2954. PMID 20298547. PMC: 2888192. | ||
Author | Angyal A, Egelston C, Kobezda T, Olasz K, László A, Glant T, Mikecz K | ||
Permission (Reusing this file) |
This file is licensed under the Creative Commons Attribution 2.0 Generic license.
|
||
Provenance InfoField |
|
File history
Click on a date/time to view the file as it appeared at that time.
Date/Time | Thumbnail | Dimensions | User | Comment | |
---|---|---|---|---|---|
current | 21:27, 18 November 2012 | 5.7 s, 512 × 512 (2.78 MB) | Open Access Media Importer Bot (talk | contribs) | Automatically uploaded media file from Open Access source. Please report problems or suggestions here. |
You cannot overwrite this file.
File usage on Commons
There are no pages that use this file.
Transcode status
Update transcode statusMetadata
This file contains additional information such as Exif metadata which may have been added by the digital camera, scanner, or software program used to create or digitize it. If the file has been modified from its original state, some details such as the timestamp may not fully reflect those of the original file. The timestamp is only as accurate as the clock in the camera, and it may be completely wrong.
Short title | Additional file 2 |
---|---|
Author | |
Usage terms | http://creativecommons.org/licenses/by/2.0/ |
Image title | Supplemental Video 1. Localization and motility of fluorescent T and B cells in the popliteal LN of a SCID mouse following their transfer from arthritic BALB/c mice. Donor T cells were labeled with CellTracker Red (CMTPX) and non-T cells (~90% B cells) with CellTracker Green (CMFDA), and mixed at a ratio of 1:2 prior to injection into the SCID mouse. The popliteal LN was subjected to TPM imaging on day 7 after cell transfer. Z series of images were acquired from the LN in vivo. Autofluorescent subcapsular sinus macrophages (light blue) are seen in the top layer of the cortex. B cells (green) localize in the more superficial, while T cells (red) in the deeper areas of the LN. Most T and B cells exhibit a polarized shape and 'random' movement. Imaging depth: 87 ?m; time elapsed: 9.5 min. |
Software used | Xiph.Org libtheora 1.1 20090822 (Thusnelda) |
Date and time of digitizing | 2010 |