File:Computational-Analysis-of-the-Spatiotemporal-Coordination-of-Polarized-PI3K-and-Rac1-Activities-in-pone.0021293.s010.ogv
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Computational-Analysis-of-the-Spatiotemporal-Coordination-of-Polarized-PI3K-and-Rac1-Activities-in-pone.0021293.s010.ogv (Ogg Theora video file, length 16 s, 357 × 195 pixels, 188 kbps, file size: 363 KB)
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[edit]DescriptionComputational-Analysis-of-the-Spatiotemporal-Coordination-of-Polarized-PI3K-and-Rac1-Activities-in-pone.0021293.s010.ogv |
English: The distribution of PI3K activity in an MEF under PDGF stimulation followed by LY inhibition. The fluorescence images representing the subcellular distribution of PI3K activity were overlaid on the DIC images of the MEFs. PDGF stimulation induced a significant increase of free end dynamics accompanied by an increase of PH-Akt-GFP fluorescence (PI3K activity). Adding LY inhibited PI3K activity at the free end and caused its retraction within 10 min. |
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Source | Movie S3 from Lu S, Kim T, Chen C, Ouyang M, Seong J, Liao X, Wang Y (2011). "Computational Analysis of the Spatiotemporal Coordination of Polarized PI3K and Rac1 Activities in Micro-Patterned Live Cells". PLOS ONE. DOI:10.1371/journal.pone.0021293. PMID 21738630. PMC: 3124492. | ||
Author | Lu S, Kim T, Chen C, Ouyang M, Seong J, Liao X, Wang Y | ||
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 22:12, 30 October 2012 | 16 s, 357 × 195 (363 KB) | Open Access Media Importer Bot (talk | contribs) | Automatically uploaded media file from Open Access source. Please report problems or suggestions here. |
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This file contains additional information such as Exif metadata which may have been added by the digital camera, scanner, or software program used to create or digitize it. If the file has been modified from its original state, some details such as the timestamp may not fully reflect those of the original file. The timestamp is only as accurate as the clock in the camera, and it may be completely wrong.
Author | Lu S, Kim T, Chen C, Ouyang M, Seong J, Liao X, Wang Y |
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Usage terms | http://creativecommons.org/licenses/by/3.0/ |
Image title | The distribution of PI3K activity in an MEF under PDGF stimulation followed by LY inhibition. The fluorescence images representing the subcellular distribution of PI3K activity were overlaid on the DIC images of the MEFs. PDGF stimulation induced a significant increase of free end dynamics accompanied by an increase of PH-Akt-GFP fluorescence (PI3K activity). Adding LY inhibited PI3K activity at the free end and caused its retraction within 10 min. |
Software used | Xiph.Org libtheora 1.1 20090822 (Thusnelda) |
Date and time of digitizing | 2011 |