File:Analysis of the BMP signaling pathway.jpg
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Analysis of the BMP signaling pathway. (A) Quantification of P-SMAD1/5/8 immunohistochemistry on sagittal sections of musculus flexor carpi ulnaris of Noggin+/+ and Noggin−/− mice at the three different stages investigated. Values plotted as mean ± SEM; n = 5; *p < 0.05. Representative immunohistochemistry for P-SMAD1/5/8 at 16.5 dpc in Noggin+/+ (B) and Noggin−/− muscle (C). Enlargement of muscle area delineated in black in B’ and C’. Muscle is delineated in red, cartilage and bone in blue. Scale bar: 100 μm. (D) WB analysis of the levels of P-SMAD1/5/8 compared to total SMAD1/5/8 and (E) IDs, normalized for GAPDH. (F) Quantification of the WB, data are representative of 3 independent experiments and values are expressed as mean ± sd; *p < 0.05, **p < 0.01. (G) qPCR analysis of BMP target genes at E16.5 dpc. Values plotted as mean ± SEM; n = 5; *p < 0.05. |
| Date | |
| Source | https://www.nature.com/articles/srep31949 Costamagna, D., Mommaerts, H., Sampaolesi, M. et al. Noggin inactivation affects the number and differentiation potential of muscle progenitor cells in vivo. Sci Rep 6, 31949 (2016). https://doi.org/10.1038/srep31949 |
| Author | Costamagna, D., Mommaerts, H., Sampaolesi, M. et al |
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| current | 18:28, 16 December 2024 | | 944 × 1,526 (198 KB) | Rasbak (talk | contribs) | {{Information |Description=Analysis of the BMP signaling pathway. (A) Quantification of P-SMAD1/5/8 immunohistochemistry on sagittal sections of musculus flexor carpi ulnaris of Noggin+/+ and Noggin−/− mice at the three different stages investigated. Values plotted as mean ± SEM; n = 5; *p < 0.05. Representative immunohistochemistry for P-SMAD1/5/8 at 16.5 dpc in Noggin+/+ (B) and Noggin−/− muscle (C). Enlargement of muscle area delineated in black in B’ and C’. Muscle is delineated in red,... |
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