File:ABCG2 with plasma membrane.jpg
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Captions
Captions
The transmembrane ABCG2 channel, including the simulated position of the plasma membrane.
Summary
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| Description |
English: The ABCG2 channel is a human multidrug transporter. Cholesterol molecules play an integral role in the function of the protein. The gap on the intracellular side is the binding pocket where drugs first bind. The intracellular loops also possess nucleotide-binding pockets that allow ATP hydrolysis to pump drugs to the extracellular environment.
Taylor et al., “Structure of the Human Multidrug Transporter ABCG2.” Visualizations were created using the Chimera program. UCSF Chimera--a visualization system for exploratory research and analysis. Pettersen EF, Goddard TD, Huang CC, Couch GS, Greenblatt DM, Meng EC, Ferrin TE. J Comput Chem. 2004 Oct;25(13):1605-12. |
| Date | |
| Source | Own work |
| Author | DSchlink15 |
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 04:36, 29 April 2022 | | 586 × 668 (92 KB) | DSchlink15 (talk | contribs) | Uploaded own work with UploadWizard |
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