File:A-conserved-leucine-occupies-the-empty-substrate-site-of-LeuT-in-the-Na+-free-return-state-ncomms11673-s2.ogv
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A-conserved-leucine-occupies-the-empty-substrate-site-of-LeuT-in-the-Na+-free-return-state-ncomms11673-s2.ogv (Ogg Theora video file, length 3.3 s, 640 × 480 pixels, 6.17 Mbps, file size: 2.45 MB)
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[edit]DescriptionA-conserved-leucine-occupies-the-empty-substrate-site-of-LeuT-in-the-Na+-free-return-state-ncomms11673-s2.ogv |
English: Supplementary Movie 1 The movie depicts the transition between two LeuT return states in pH 6.5 structure Molecule A and B, zoomed in at the extracellular side. The movie was prepared by 'morphing' from Molecule A to Molecule B and back. TM1b (red cartoon) fluctuates to some extent at the extracellular side, however Leu25 (red sticks) is stable at its position. The major difference between the two molecules is Asn27 (orange sticks), which interacts with either the Glu290 side chain (yellow sticks) or the TM7 backbone next to Glu290 |
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Source | Video file from Malinauskaite L, Said S, Sahin C, Grouleff J, Shahsavar A, Bjerregaard H, Noer P, Severinsen K, Boesen T, Schiøtt B, Sinning S, Nissen P (2016). "A conserved leucine occupies the empty substrate site of LeuT in the Na+-free return state". Nature Communications. DOI:10.1038/ncomms11673. PMID 27221344. PMC: 4894957. | ||
Author | Malinauskaite L, Said S, Sahin C, Grouleff J, Shahsavar A, Bjerregaard H, Noer P, Severinsen K, Boesen T, Schiøtt B, Sinning S, Nissen P | ||
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This file is licensed under the Creative Commons Attribution 4.0 International license.
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 19:46, 27 October 2016 | 3.3 s, 640 × 480 (2.45 MB) | Open Access Media Importer Bot (talk | contribs) | Automatically uploaded media file from Open Access source. Please report problems or suggestions here. |
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Short title | Supplementary Movie 1 |
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Author | Malinauskaite L, Said S, Sahin C, Grouleff J, Shahsavar A, Bjerregaard H, Noer P, Severinsen K, Boesen T, Schiøtt B, Sinning S, Nissen P |
Usage terms | http://creativecommons.org/licenses/by/4.0/ |
Image title | The movie depicts the transition between two LeuT return states in pH 6.5 structure Molecule A and B, zoomed in at the extracellular side. The movie was prepared by 'morphing' from Molecule A to Molecule B and back. TM1b (red cartoon) fluctuates to some extent at the extracellular side, however Leu25 (red sticks) is stable at its position. The major difference between the two molecules is Asn27 (orange sticks), which interacts with either the Glu290 side chain (yellow sticks) or the TM7 backbone next to Glu290 |
Software used | Xiph.Org libtheora 1.1 20090822 (Thusnelda) |
Date and time of digitizing | 2016-05-25 |