File:The breast- its anomalies, its diseases, and their treatment (1917) (14570368668).jpg

Identifier: breastitsanomali00deav (find matches)
Title: The breast: its anomalies, its diseases, and their treatment
Year: 1917 (1910s)
Authors: Deaver, John B. (John Blair), 1855-1931
Subjects: Breast Breast X-rays Breast Diseases Breast Neoplasms Radiotherapy
Publisher: Philadelphia, P. Blakiston's Son & Co
Contributing Library: Francis A. Countway Library of Medicine
Digitizing Sponsor: Open Knowledge Commons

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, JMiiller and others, all of whom vigorously oppose Borsts idea that they are the startingpoint of carcinoma, and point out, as we have done, that they differ essentially, in appearance, fromcarcinoma cells and that no intermediate steps between them and carcinoma cells can be found. Kururecognized them in fibro-epithelial tumors, and frequently found them in the mammary glands of children.They have also been obser\ed in sweat glands, von Saar thinks that they arise through simple benignproliferation and agrees with Thiele in believing that they differ from the normal epithelium only inhaving a greater vegetative activity and a shorter life duration. They probably comprise the greaternumber of cells with which the smaller cysts are filled in Schimmelbuschs disease or maladie de Reclus,but which later melt away to cause the turbid and dark-colored contents of the cysts. In our cases ofassociated abnormal involution and cancer, these cells were present to form numerous large or smaller
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Fig. 120.—A group of dilated alveoli in a case of well-marked abnormal involution of thebreast. rounded circumscribed masses some of which were in close juxtaposition to the carcinoma cells, or insome cases even invaded by them, but the difference between them and the carcinoma cells was usuallystriking. C. Alveolar Sprouts and Buds.—Many of our sections showed appearances closely resembling evolu-tional or developmental processes such as are universal in the breast at puberty. They consist of groupsof cells, forming striking objects that at once arrest the eye when the section is examined beneath themicroscope. Each group is obviously a bud or sprout from the glandular tissue, and the groups occurin collections that suggest an effort at lobule formation. Each bud is a clavate or flask-shaped termi-nation of parenchymatous tissue, formed of a solid mass of cells, the outer of which stand regularly uponthe subjacent connective tissue, without any definite basement membrane, the inn

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