File:The Journal of nervous and mental disease (1874) (14598089469).jpg

Identifier: journalofnervous48ameruoft (find matches)
Title: The Journal of nervous and mental disease
Year: 1874 (1870s)
Authors: American Neurological Association
Subjects: Nervous system Psychology, Pathological
Publisher: Baltimore (etc.) Williams & Wilkins (etc.)
Contributing Library: Internet Archive
Digitizing Sponsor: Internet Archive

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degree of lymphocytic infiltration of the lymphspaces and possibly some slight increase of the connective-tissuecells. The blood vessels show the usual hyperemia with normaiwalls. Anterior Horn.—The branches of the posterior spinal arteriesshow little evidence of infiltration of the Virchow-Robin lymphspaces, while those of the lateral arteries contain much more, andthose of the anterior spinal group occupy a position intermediatewith the others. Vessel sheath infiltration is not as striking afeature as in those cases described before. As the result of this onefinds the typical pathological changes in the zona intermedia moremarked than in either the anterior or posterior horns. In the nervetissue, in both the gray and white matter, signs of considerableedema are seen. 208 HUBERT S. HOWE Ganglionic Cells.—In the anterior horn there has apparentlybeen ho destruction of the motor cells, as these are present in normalmmibers, but all show acute cloudy swelling of considerable degree.
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Fig. 12. Section of anterior horn. Hinnan case No. 507, X 300, showingsingle vacuolization without neuronophagy or chromotolysis. Many of the ganglion cells show one or more large vacuoles inthe cytoplasm. There is no increase in the neuroglia cells and noinvasion of the tissue with lymphocytes or polyblasts. Neuro- PATHOLOGV OF POLIOMYELITIS 209 nophagy is not present. In the zona intermedia the neurogha cellsare increased in number and many polyblasts are present. Here theswollen nerve cells stain less deeply, the nuclei appear paler and a 1 ,0 ■■ •. ^ ( 3 S** . * « V * ^ •a _ . ^■ 1 ■i ■•^ ■ & ■ ■■ . - . Si 1 ■ V . ■ % ! ■ .^ .- i.- ^^^ffi^ Ifc « Fig. 13. Section of anterior horn. Human case No. 507, X 300, showingmuhiple vacuolization without neuronophagy or chromatolysis. number of the cells have undoubtedly disappeared and evidences ofbeginning neuronophagy, in the main by means of glia cells, areamply evident. (Figs. 12 and 13.) 2I

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