File:Sickle cell gene under selection.png
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English: The calculated rate at which the frequency of a newly mutated sickle-cell gene will increase in a population exposed to intense malarial selection. The change over generations in the sickle-cell heterozygote (Aa) + homozygote (AA) frequency in the adult population that would occur from a low level (recent mutation) or a high level (unlikely founder event in a small population) when the fitnesses of the normal homozygote, sickle-cell heterozygote and sickle-cell homozygote are 0.95, 1.19 and 0.30, respectively. Based on data published in Allison AC (1955). "Aspects of polymorphism in man". Cold Spring Harb Symp Quant Biol 20: 239-251. |
| Source | Own work |
| Author | TimVickers |
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I, the copyright holder of this work, release this work into the public domain. This applies worldwide. In some countries this may not be legally possible; if so: I grant anyone the right to use this work for any purpose, without any conditions, unless such conditions are required by law. |
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
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| current | 03:51, 28 March 2010 | | 553 × 412 (7 KB) | TimVickers (talk | contribs) | {{Information |Description={{en|1=The calculated rate at which the frequency of a newly mutated sickle-cell gene will increase in a population exposed to intense malarial selection. The change over generations in the sickle-cell heterozygote (Aa) + homozy |
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