File:Redox-Neutral 1,3-Diol Synthesis by Base-Promoted Diastereoselective Alcohol–Aldolization (MédiHAL 2953871).jpg

From Wikimedia Commons, the free media repository
Jump to navigation Jump to search

Redox-Neutral_1,3-Diol_Synthesis_by_Base-Promoted_Diastereoselective_Alcohol–Aldolization_(MédiHAL_2953871).jpg (455 × 102 pixels, file size: 10 KB, MIME type: image/jpeg)

Captions

Captions

In order to prepare more efficiently key 1,3-diol fragments, we have devised a base-promoted redox-neutral condensation of ketones with alcohols.

Summary

[edit]
Description
English: In order to prepare more efficiently key 1,3-diol fragments, we have devised a base-promoted redox-neutral condensation of ketones with alcohols. This diastereoselective alcohol–aldolization enables bypassing the classical oxidation and reduction steps necessary for the preparation of this crucial backbone by an overall redox-neutral formal borrowing hydrogen process. The starting alcohols constitute both the precursors of the in situ generated reactive aldehydes and the hydride source necessary for the chemoselective reduction of the aldol adduct intermediates.
Date Taken on 18 September 2020
Source Redox-Neutral 1,3-Diol Synthesis by Base-Promoted Diastereoselective Alcohol–Aldolization
Author

Na Shao, Jean Rodriguez, Adrien Quintard

Adrien Quintard   wikidata:Q81717626
 
Description researcher
Authority file
creator QS:P170,Q81717626
institution QS:P195,Q30295259
institution QS:P195,Q2302586
institution QS:P195,Q3152386
institution QS:P195,Q280413
Keywords
InfoField
Hydrogen transfer; Synthetic economies; Polyols; Cascade; Redox-Neutral

Licensing

[edit]
Public domain
This work is in the public domain in France for one of the following reasons:
  • Its author (or the last of its authors in the case of a collaboration work) died more than 70 years ago (CPI art. L123-1) and did not benefit from any copyright extension (CPI art. L123-8, L123-9 and L123-10)[1];
  • It is an anonymous or pseudonymous work (the identity of the author has never been disclosed) or a collective work[2] and more than 70 years have passed since its publication (CPI art. L123-3);
  • It is the recording of an audiovisual or musical work already in the public domain, and more than 50 years have passed since the performance or the recording (CPI art. L211-4).
Please note that moral rights still apply when the work is in the public domain. They encompass, among others, the right to the respect of the author's name, quality and work (CPI art. L121-1). Attribution therefore remains mandatory.
  1. ↑ Copyright extensions must be considered only in the case of musical works and of authors Mort pour la France (died during conflict, in the service of France). In other cases, they are included in the 70 years post mortem auctoris length (see this statement of the Cour de Cassation).
  2. ↑ The collective work status is quite restrictive, please make sure that it is actually established.

العربية ∙ English ∙ español ∙ français ∙ 日本語 ∙ 한국어 ∙ македонски ∙ русский ∙ Tiếng Việt ∙ 简体中文 ∙ 繁體中文 ∙ +/−

File history

Click on a date/time to view the file as it appeared at that time.

Date/TimeThumbnailDimensionsUserComment
current19:58, 19 December 2024Thumbnail for version as of 19:58, 19 December 2024455 × 102 (10 KB)OptimusPrimeBot (talk | contribs)#Spacemedia - Upload of https://media.hal.science/hal-02953871/file/Graph_AQ_16.jpg via Commons:Spacemedia

You cannot overwrite this file.

There are no pages that use this file.

Metadata

This file contains additional information such as Exif metadata which may have been added by the digital camera, scanner, or software program used to create or digitize it. If the file has been modified from its original state, some details such as the timestamp may not fully reflect those of the original file. The timestamp is only as accurate as the clock in the camera, and it may be completely wrong.

Retrieved from "https://commons.wikimedia.org/w/index.php?title=File:Redox-Neutral_1,3-Diol_Synthesis_by_Base-Promoted_Diastereoselective_Alcohol–Aldolization_(MédiHAL_2953871).jpg&oldid=973604241"