File:Neristatin 1.svg
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DescriptionNeristatin 1.svg |
English: Chemical structure of neristatin 1, a polyketide isolated from Bugula neritina. Ki for protein kinase C: 21.2 nM (PDBu: 0.53 nM). Absolute stereochemistries of northern hemisphere of neristatin were firstly assigned as 3(R), 5(R), 7(S), 9(S), and 15(R) based upon the known absolute stereochemistry of the related bryostatins, but X-ray crystal structure in the patent document indicates that absolute stereochemistry at position C-9 (hemiketal position) is R.
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Source | Own work | ||||
Author | Charlesy | ||||
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Annotations InfoField | This image is annotated: View the annotations at Commons |
Position C-9.
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 00:31, 21 November 2017 | 572 × 436 (31 KB) | Charlesy (talk | contribs) | Stereochemistry at C-9. | |
07:58, 27 June 2012 | 465 × 362 (18 KB) | Charlesy (talk | contribs) | {{Information |Description ={{en|1=Chemical structure of neristatin 1, a polyketide isolated from ''Bugula neritina''. {{cite journal|title= Antineoplastic agents. 224. Isolation and structure of neristatin 1|author=Pettit, G. R.; Gao, F.; Herald,... |
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Width | 572.2168 |
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Height | 435.78125 |