File:Molecules-27-02259-g005-550.webp
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Captions
Captions
sotorasib
Summary
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| Description |
English: Figure 5. Overview of mechanism of action of sotorasib (the “x” on the arrows indicates process inhibition). RTK: tyrosine kinase receptor. PTPN11: tyrosine-protein phosphatase non-receptor type 11. SOS1: Son of sevenless. GEF: guanine nucleotide exchange factor. GAP: GTPase-activating protein. KRAS: GTPase KRas. GDP: guanosine-5’-diphosphate. GTP: guanosine-5’-triphosphate. RAF: proto-oncogene serine/threonine-protein kinase. MEK: mitogen-activated protein kinase kinase. ERK: mitogen-activated protein kinase. PI3K: phosphatidylinositol 3-kinase. AKT: protein kinase B. mTOR: mammalian target of rapamycin. Created with BioRender.com based on information in Ref. [167]. |
| Date | |
| Source | https://www.mdpi.com/1420-3049/27/7/2259 |
| Author | Sochacka-Ćwikła, A.; Mączyński, M.; Regiec, A |
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 20:18, 3 May 2024 | | 550 × 335 (25 KB) | Ozzie10aaaa (talk | contribs) | Uploaded a work by Sochacka-Ćwikła, A.; Mączyński, M.; Regiec, A from https://www.mdpi.com/1420-3049/27/7/2259 with UploadWizard |
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