File:MiRNA-biogenesis.jpg

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Summary

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Description
English: Overview of microRNA processing in animals, from transcription to the formation of the effector complex. There are two pathways, one for microRNAs from independent genes and one for intronic microRNAs.

Enzymes in the picture:
Drosha, Pasha (pri-miRNA → pre-miRNA)
Spliceosome (pre-mRNA → intron lariat)
Debranching enzyme (intron lariat → RNA that can fold into pre-miRNA)
RAN-GTP, Exportin-5 (export from nucleus)
Dicer (pre-miRNA → miRNA)

Abbrevations:
pri-miRNA = primary microRNA transcript
pre-mRNA = precursor messenger RNA
pre-miRNA = precursor microRNA
miRNA = microRNA
miRNA* = antisense microRNA
miRNP = microRNA ribonucleoprotein
עברית: תהליכים בסינתזה של MicroRNA
Date
Source

Own work (Original text: I created this work entirely by myself.)

References:

  • Esquela-Kerscher A, Slack FJ (2006) Oncomirs — microRNAs with a role in cancer. Nat Rev Cancer 6: 259–69. PubMed
  • Okamura K, Hagen JW, Duan H, Tyler DM, Lai EC (2007) The mirtron pathway generates microRNA-class regulatory RNAs in Drosophila. Cell 130: 89–100. PubMed
Author Narayanese (talk)
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This biology image could be re-created using vector graphics as an SVG file. This has several advantages; see Commons:Media for cleanup for more information. If an SVG form of this image is available, please upload it and afterwards replace this template with {{vector version available|new image name}}.


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Licensing

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Narayanese at English Wikipedia, the copyright holder of this work, hereby publishes it under the following license:
w:en:Creative Commons
attribution share alike
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Attribution: Narayanese at English Wikipedia
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Original upload log

[edit]
The original description page was here. All following user names refer to en.wikipedia.
  • 2009-04-13 18:00 Narayanese 1520×1610× (356456 bytes) removed PolII from picture
  • 2009-04-13 17:33 Narayanese 1520×1610× (379131 bytes) {{Information |Description = microRNA biosynthesis |Source = I created this work entirely by myself. |Date = 13 April 2009 |Author = ~~~ |other_versions = }}


The original description page was here. All following user names refer to he.wikipedia.
  • 2009-12-03 08:34 Adiel lo 1520×1610× (356456 bytes) ==תקציר== {{מידע| |תיאור=תהליכים בסינתזה של [[MicroRNA]] |מקור=ויקיפדיה אנגלית [http://en.wikipedia.org/wiki/File:MiRNA-biogenesis.jpg[ |תאריך יצירה= |יוצר=http://en.wikipedia.org/wiki/User:Nar

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Date/TimeThumbnailDimensionsUserComment
current08:23, 28 June 2012Thumbnail for version as of 08:23, 28 June 20121,520 × 1,610 (348 KB)OgreBot (talk | contribs)(BOT): Reverting to most recent version before archival
08:22, 28 June 2012Thumbnail for version as of 08:22, 28 June 20121,520 × 1,610 (370 KB)OgreBot (talk | contribs)(BOT): Uploading old version of file from en.wikipedia; originally uploaded on 2009-04-13 17:33:21 by Narayanese
09:49, 6 January 2012Thumbnail for version as of 09:49, 6 January 20121,520 × 1,610 (348 KB)Matanya (talk | contribs) {{BotMoveToCommons|he.wikipedia|year={{subst:CURRENTYEAR}}|month={{subst:CURRENTMONTHNAME}}|day={{subst:CURRENTDAY}}}} {{Information |Description={{he|תהליכים בסינתזה של he:MicroRNA}} |Source=Transferred from [http://he.wikipedia.o

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