File:Manual of antenatal pathology and hygiene - the foetus (1902) (14598271327).jpg

Identifier: manualofantenata00ballrich (find matches)
Title: Manual of antenatal pathology and hygiene : the foetus
Year: 1902 (1900s)
Authors: Ballantyne, John William, 1861-1923
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Publisher: New York : William Wood
Contributing Library: University of California Libraries
Digitizing Sponsor: MSN

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his articleon .syphilitic jaundice (Bull. Soc. Anal, dc Paris, xxiv. 66,1849); sincethen many monographs dealing with the same subject have appeared,among which that by Lucien Hudelo (Contrihution a Iltude des lesionsdufoie dans la si/philis hMditaire, Varis, 1890) may he singled outfor special mention; but Gubler it was who broke fresh ground inthis direction—a memorable name and date therefore—Gubler IS.tO.To be quite exact it was in 1847 that Gubler first noted .specialchanges in the liver of the sypliilitic new-born infant, but thepublication of the fact was in 1849. What, then, are the changesmet with in the foetal liver in syphilis ? In the first place, lest I by any cliance omit to make the state-ment, tlie liver may show no alterations whatever, exhibiting only tlienaked-eye and microscopic cliaracters common to all new-born infants;in other cases in which the ftctus has died in utero, the organ willreveal the aiipearances due to macerative change, and these may 1 Plate x
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PATHOLOGY OF F(ETAL SYPHILIS 233 entirely obscure any specific peculiarities. This statement is truenot only o^ tlir- liver but also of all the organs in foetal syphilis. In tht second place, the liver may be the seat of very specialchanges, macroscopic and microscopic. To the liver thus altered bysyphilis the French writers have given the names foie silex (Hintliver) and foie silex avec grains de semoule (Hint liver withsemolina grains); the two names to some extent indicate twodiHerent alterations, for the flint liver may show none of the semolina grains; but it is common to find the two groups oflesions combined in the same liver, the semolina change being theusual concomitant of the flinty ( cest la satellite habituelle de lalision silex, Hudelo). Some years ago I obtained from an lui-doubledly syphilitic fcetus the liver which is produced in Ilate X.,it exhibits very clearly the semolina grain appearance. The flintliver ( foie silex ) is larger and heavier than normal and its mar

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