File:How do tumors cross the blood vessel barrier?.jpg

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Captions

Captions

Microscope images show the process by which tumors metastasize.

Summary

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Description
Polski: Zdjęcie mikroskopowe po lewej stronie przedstawia komórki śródbłonka (ludzka linia komórkowa HLEC) oraz znajdujący się na niej sferoid utworzony przez komórki ziarniszczaka jajnika (ludzka linia nowotworowa KGN). Na zdjęciu po prawej stronie obserwujemy dziurę w monowarstwie komórek śródbłonka wytworzoną przez komórki ziarniszczaka jajnika. W ten sposób nowotwór pokonuje barierę naczyń krwionośnych i przerzutuje. Komórki HLEC są wybarwione barwnikiem Green CMFDA. Zdjęcia wykonane w mikroskopie fluorescencyjnym. Zostały wykonane w Zakładzie Fizjologii i Toksykologii Rozrodu w Instytucie Zoologii i Badań Biomedycznych Uniwersytetu Jagiellońskiego, Polska.
English: The microscope image on the left shows endothelial cells (HLEC human cell line) and on endothelial cells there is a spheroid formed by ovarian granulosa tumor cells (KGN human tumor cell line). In the photo on the right, we observe a hole in endothelial cells created by ovarian granulosa tumor cells. In this way, the tumor overcomes the blood vessel barrier and metastasizes. HLEC cells are stained with Green CMFDA dye. Images were taken under a fluorescence microscope. Images were taken at the Department of Physiology & Toxicology of Reproduction at the Institute of Zoology and Biomedical Research, Jagiellonian University, Poland.
Date
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Author Kinga Kamińska, Justyna Gogola

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