File:Deep Brain Stimulation (DBS) of Nucleus Basalis of Meynert.jpg

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Deep_Brain_Stimulation_(DBS)_of_Nucleus_Basalis_of_Meynert.jpg (454 × 331 pixels, file size: 129 KB, MIME type: image/jpeg)

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English: Deep Brain Stimulation (DBS) of Nucleus Basalis of Meynert (NBM) in Dementia with Lewy Bodies (DLB). NBM is one group of the basal forebrain cholinergic neurons (BFCN). The degeneration of BFCN is associated with decreased cholinergic tone and cognitive deficits in DLB. NBM provides cholinergic innervations to the entire neocortex. DBS of NBM likely enhances the cholinergic tone of neocortex, leading to improved cognitive function and quality of life. Potential disease modifying mechanisms include enhanced neurogenesis and increased nerve growth factor trophic support.
Date Published: 20 August 2015.
Source Zhang Q, Kim Y-C and Narayanan NS (2015) Disease-modifying therapeutic directions for Lewy-Body dementias. Front. Neurosci. 9:293. doi: 10.3389/fnins.2015.00293 http://journal.frontiersin.org/article/10.3389/fnins.2015.00293/full
Author Zhang Q, Kim Y-C and Narayanan NS

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current14:54, 7 January 2016Thumbnail for version as of 14:54, 7 January 2016454 × 331 (129 KB)Was a bee (talk | contribs){{Information |Description={{en|1=Deep Brain Stimulation (DBS) of Nucleus Basalis of Meynert (NBM) in Dementia with Lewy Bodies (DLB). NBM is one group of the basal forebrain cholinergic neurons (BFCN). The degeneration of BFCN is associated with decre...

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