File:DARTS.png

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Original file (3,111 × 1,167 pixels, file size: 436 KB, MIME type: image/png)

Captions

Captions

DARTS: Drug Affinity Responsive Target Stability

Summary

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Description
English: An example DARTS workflow. A lysate is split into control and drug treated groups. Lysates are exposed to limited proteolysis. Upon binding a drug, a protein is stabilized and protected from digestion. Undigested proteins can then be detected via western blot (for target validation) or their absence from digests can be measured via mass spectrometry (for target identification).
Date
Source Own work
Author Sgold626

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Date/TimeThumbnailDimensionsUserComment
current21:58, 7 December 2021Thumbnail for version as of 21:58, 7 December 20213,111 × 1,167 (436 KB)Sgold626 (talk | contribs)Uploaded own work with UploadWizard

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