File:Conditional Dicer substrate formation via shape and sequence transduction with scRNAs.png
From Wikimedia Commons, the free media repository
Jump to navigation
Jump to search
Size of this preview: 760 × 599 pixels. Other resolutions: 304 × 240 pixels | 609 × 480 pixels | 974 × 768 pixels | 1,098 × 866 pixels.
Original file (1,098 × 866 pixels, file size: 26 KB, MIME type: image/png)
File information
Structured data
Captions
Summary
[edit]DescriptionConditional Dicer substrate formation via shape and sequence transduction with scRNAs.png |
English: Conditional Dicer substrate formation via shape and sequence transduction with small conditional RNAs. scRNA A·B detects mRNA detection target X (containing subsequence ‘a-b-c’), leading to production of Dicer substrate B·C targeting mRNA silencing target Y (containing independent subsequence ‘w-x-y-z’). scRNAs A·B and C are stable in the absence of X. A swaps B for X (step 1) via toehold-mediated 3-way branch migration and spontaneous dissociation. B assembles with C (step 2) via loop/toehold nucleation and 3-way branch migration to form Dicer substrate B·C. Chemical modifications (2'OMe-RNA) prevent degradation: A and part of C (dashed backbone). Image from Hochrein et al. 2013; http://pubs.acs.org/doi/abs/10.1021/ja404676x; used with permission of the American Chemical Society. |
Date | |
Source | http://pubs.acs.org/doi/abs/10.1021/ja404676x |
Author | L.M. Hochrein, M. Schwarzkopf, M. Shahgholi, P. Yin, and N.A. Pierce |
Licensing
[edit]This file is licensed under the Creative Commons Attribution 4.0 International license.
- You are free:
- to share – to copy, distribute and transmit the work
- to remix – to adapt the work
- Under the following conditions:
- attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
File history
Click on a date/time to view the file as it appeared at that time.
Date/Time | Thumbnail | Dimensions | User | Comment | |
---|---|---|---|---|---|
current | 20:46, 18 February 2015 | 1,098 × 866 (26 KB) | EditorMAK (talk | contribs) | User created page with UploadWizard |
You cannot overwrite this file.
File usage on Commons
There are no pages that use this file.
File usage on other wikis
The following other wikis use this file:
- Usage on en.wikipedia.org
Metadata
This file contains additional information such as Exif metadata which may have been added by the digital camera, scanner, or software program used to create or digitize it. If the file has been modified from its original state, some details such as the timestamp may not fully reflect those of the original file. The timestamp is only as accurate as the clock in the camera, and it may be completely wrong.
Horizontal resolution | 78.75 dpc |
---|---|
Vertical resolution | 78.75 dpc |