File:Antibodies-12-00025-g002-550.webp
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Captions
Captions
Avacopan
Summary
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| Description |
English: Figure 2. The role of complement. Activation of the alternative complement pathway results by a cascade mechanism in the synthesis of factor C5a, which after recognition of its C5aR receptor on the surface of leukocytes activates them to produce factors that mediate tissue damage. Avacopan, a C5aR agonist, inhibits C5a binding thereby blocking activation of leukocytes including neutrophils. |
| Date | |
| Source | https://www.mdpi.com/2073-4468/12/1/25 |
| Author | Paroli, M.; Gioia, C.; Accapezzato, D |
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This file is licensed under the Creative Commons Attribution 4.0 International license.
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 00:35, 15 April 2024 | | 550 × 381 (16 KB) | Ozzie10aaaa (talk | contribs) | Uploaded a work by Paroli, M.; Gioia, C.; Accapezzato, D from https://www.mdpi.com/2073-4468/12/1/25 with UploadWizard |
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