File:Action potential7.jpg

English: Axosomatic initiation of tonic and burst APs in thalamic reticular nucleus neurons. A, Simultaneous somatic (blue) and dendritic (red, 82 μm) recording of rhythmic LTS AP bursts evoked by hyperpolarizing somatic current injection from resting membrane potential (∼−70 mV). Scale as in C. B, Somatic and dendritic APs occurring during the first (i) and third (ii) LTS AP bursts. Dashed lines illustrate the delay between the peak of the somatic and dendritic spike. Scale as in D. C, As in A, but for rebound LTS AP bursts evoked by hyperpolarizing current injection into the dendrites. Dendritic current injection produces significant dendritic hyperpolarization. D, As in B, but for dendritic current injection. E, Simultaneous somatic (blue) and dendritic (red) recording from the same neuron as in A held at ∼−55 mV using d.c. injection. Tonic APs were evoked by somatic depolarizing current injections steps. F, Somatic and dendritic APs occurring at the start (i) and end (ii) of a tonic AP train. Dashed lines illustrate the delay between the peak of the somatic and dendritic spike. G, As in E, but for tonic APs evoked by dendritic depolarizing current injection. Dendritic current injection produces significant dendritic depolarization. Note that dendritic amplitude of APs evoked by dendritic current injection does not differ from dendritic APs evoked by somatic current injection. Scale as in E. H, As in F, but for dendritic current injection. Scale as in F.