File:A text-book of human physiology (1906) (14583706970).jpg

Identifier: textbookofhumanp00tige (find matches)
Title: A text-book of human physiology
Year: 1906 (1900s)
Authors: Tigerstedt, Robert, 1853-1923 Murlin, John R. (John Raymond), b. 1874, tr
Subjects: Physiology
Publisher: New York and London, D. Appleton and Co.
Contributing Library: Columbia University Libraries
Digitizing Sponsor: Open Knowledge Commons

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sion in the plasma, is high, the globulinwill be forced out of its alkali compound. If, however, the blood comes intosuch relations that the car))on dioxide tension falls, the globulins again suc-ceed to their rights and the carbon dioxide leaves the alkali (Torup). As already observed, carbon dioxide occurs also in the blood corpusclesin the form of dissociable compounds. It is very probable that the globulin-alkali compounds of the blood corpuscles act in the same way as those of the THE BLOOD GASES 339 serum. It should be added, however, that the curve of CO, absorption forthe corpuscles exhibits a much greater dependence upon the partial pressureof CO2 than that for the serum (Bohr). The constituent most activelyconcerned here again is the haemoglobin (Fig. 133). Hcemoglobin therefore can combine carbon dioxide as well as oxygen. Weare not yet clear just how this takes place. Bohr has shown that the absorp-tion of carbon dioxide by haemoglobin free of alkalies is influenced little
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Fig. 132.—The absorption of carbon dioxide in a solution of hsemoglobin, after Bohr, 1.76 per cent solution; 3.8 per cent solution. The abscissa- represent the pres-sure to which the gas was subjected, the ordinates the amount of carbon dioxide in c.c.absorbed by 1 g. of haemoglobin. or not at all by oxygen. For this reason he assumes that the two gases arecombined with different parts of the haemoglobin molecule—the oxygen withthe pigment nucleus, and the carbon dioxide with the proteid component. D. THE QUANTITY OF BLOOD GASES The content of gases is very different in arterial and venous blood. Anal-yses of the gases in dogs blood, carried out under the direction of Ludwig andPfliiger, give us, according to the summary of Zuntz, the following averagepercentages: arterial blood, 18.3 vols, per cent oxygen and 38.3 vols, per cent£ar))on dioxide. By very rapid extraction of the gases Pfliiger obtained forarterial blood 22.6 vols, per cent oxygen and 34.3 vols, per cent carbon diox

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