File:12943 2021 1311 Fig2 HTML.webp

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Captions

Captions

Trans-amplifying RNA (taRNA) The replicase transcribes a negative strand RNA with the 3′-nontranslated region (NTR).

Summary

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Description
English: Trans-amplifying RNA (taRNA) The replicase transcribes a negative strand RNA with the 3′-nontranslated region (NTR). In turn, it uses the negative strand RNA as a template to transcribe a positive strand RNA from the 5′-NTR region. A promoter (arrow) initiates transcription into mRNA. Vaccine antigens come from the mRNA, which is mediated by cytoplasmic ribosomes.
Date
Source Wang, Y., Zhang, Z., Luo, J. et al. mRNA vaccine: a potential therapeutic strategy. Mol Cancer 20, 33 (2021). https://doi.org/10.1186/s12943-021-01311-z
Author Yang Wang, Ziqi Zhang, Jingwen Luo, Xuejiao Han, Yuquan Wei, and Xiawei Wei

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current03:26, 14 August 2021Thumbnail for version as of 03:26, 14 August 20211,944 × 705 (186 KB)Guest2625 (talk | contribs)Uploaded a work by Yang Wang, Ziqi Zhang, Jingwen Luo, Xuejiao Han, Yuquan Wei, and Xiawei Wei from Wang, Y., Zhang, Z., Luo, J. et al. mRNA vaccine: a potential therapeutic strategy. Mol Cancer 20, 33 (2021). https://doi.org/10.1186/s12943-021-01311-z with UploadWizard

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